Welcome to BCF homepage at http://bcf.assic.sinica.edu.tw/.
The Biophysics Core Facility (BCF) of the Scientific Instrument Center, Academia Sinica, is located in Room 402 in the Institute of Biological Chemistry. Previously known as Molecular Characterization Core, the facility, in operation since 2008, is the home of several state-of-art instruments, providing technical support for facility users in terms of training, scheduling, workshops, user certification, trouble shooting and instrument maintenance. To learn about BCF's training courses, please visit our Courses website.
BCF currently houses the following instruments: analytical ultracentrifuge (Beckman XL-I), surface plasmon resonance biosensors (GE Biacore T200, AutoLab Esprit ESPR), bio-layer interferometer (ForteBIO Octet RED96,), isothermal titration calorimeter (GE iTC200), differential scanning calorimeter (TA Nano DSC III), dynamic and static light scattering spectrometer (Malvern Zetasizer Nano) and capillary isoelectric focusing platform (ProteinSimple NanoPRO 1000); in addition, on sharing basis, a stopped-flow circular dichroism spectrometer (Aviv CD 202) with Institute of BioMedical Sciences, a differential scanning calorimeter (GE VP-DSC) with Institute of Physics, a surface plasmon resonance biosensor (Biacore T100) with Institute of Plant and Microbial Biology and an analytical ultracentrifuge (Beckman AUC XL-A) with Institute of Biological Chemistry. In combination of results from each instrument, researchers gain insights into the thermodynamics, kinetics and structural information for interactions of biological molecules.
BCF User Committee members (2014-):
Dr. Chun-Hung Lin (chairman, Institute of Biological Chemistry)
Dr. Chinpan Chen (Institute of BioMedical Sciences)
Dr. Hung-Ta Chen (Institute of Molecular Biology)
Dr. Jen-Tse Joseph Huang (Institute of Chemistry)
Dr. Keng-Hui Lin (Institute of Physics)
Dr. Che Alex Ma (Genomics Research Center)
Dr. Shih-Long Tu (Institute of Plant and Microbial Biology )
Dr. Kuo-Chen Yeh (Agricultural Biotechnology Research Center)