Welcome to BCF homepage at http://bcf.assic.sinica.edu.tw/.
The Biophysics Core Facility (BCF) of the Scientific Instrument Center, Academia Sinica, is located in Room 402 in the Institute of Biological Chemistry. Previously known as Molecular Characterization Core, the facility, in operation since 2008, is the home of several state-of-art instruments, providing technical support for facility users in terms of training, scheduling, workshops, user certification, trouble shooting and instrument maintenance. To learn about BCF's training courses, please visit our Courses website.
BCF currently houses the following instruments: analytical ultracentrifuge (Beckman XL-I), surface plasmon resonance biosensors (GE Biacore T200), bio-layer interferometer (ForteBIO Octet RED96,), isothermal titration calorimeter (GE MicroCal iTC200), differential scanning calorimeter (TA Nano DSC III, Malvern MicroCal VP-Capillary DSC), dynamic and static light scattering spectrometer (Malvern Zetasizer Nano) and capillary isoelectric focusing platform (ProteinSimple NanoPRO 1000); in addition, on sharing basis, a differential scanning calorimeter (GE MicroCal VP-DSC) with Institute of Physics, a surface plasmon resonance biosensor (Biacore T100) with Institute of Plant and Microbial Biology and an analytical ultracentrifuge (Beckman AUC XL-A) with Institute of Biological Chemistry. In combination of results from each instrument, researchers gain insights into the thermodynamics, kinetics and structural information for interactions of biological molecules.
BCF User Committee members (2016-):
Dr. Chun-Hung Lin (chairman, Institute of Biological Chemistry)
Dr. Cheng-Hsun Ho (Agricultural Biotechnology Research Center)
Dr. Kuo-Chiang Hsia (Institute of Molecular Biology)
Dr. Jen-Tse Joseph Huang (Institute of Chemistry)
Dr. Tsung-Lin Li (Genomics Research Center)
Dr. Ru-Chi Shieh (Institute of BioMedical Sciences)
Dr. Shih-Long Tu (Institute of Plant and Microbial Biology)